Specification:
Narigin 80-98% HPLC

Antioxidant
Studies have shown that naringin from grapefruit extract can increase the activity of superoxide dismutase (SOD) and catalase (CAT) in the liver, reduce the content of mitochondrial hydrogen peroxide in the liver cells and increase the concentration of vitamin E in the plasma. Naringin can also induce the expression of antioxidant enzyme mRNA.
Naringin has a mild inhibitory effect on lipid peroxidation in the rat brain and kidney tissue homogenate. The presence of phenolic hydroxyl groups in the molecular structure is an important factor in the antioxidant effect of naringin, suggesting that the low inhibitory effect is related to a small phenolic hydroxyl number in its structure.
Reducing blood lipid
In vivo studies have shown that naringin from grapefruit extract has the effect of lowering cholesterol, which may be achieved by inhibiting the activity of cholesterol synthase (such as HMG-CoA ~ DACAT), reducing the synthesis of cholesterol in the body, promoting cholesterol breakdown, reducing low density lipoprotein (LDL).
Scientists fed male rats with high cholesterol diet and naringin, the rat plasma, liver lipid content and neutral steroid excretion are determined after 42 days, the test results show that naringin cannot significantly improve plasma triglyceride level, but can significantly reduce plasma and liver cholesterol levels, and reduce the amount of steroid excretion. The levels of HMG-CoA and ACAT in the naringin-treated group were significantly lower than the control group.
Naringin reduces the rate of cholesterol biosynthesis in the liver by inhibiting HMG-CoA, increases steroid excretion and reduces plasma cholesterol. At the same time, histopathological analysis showed that naringin could relieve the damage of vascular wall caused by high fat diet and had a certain effect on reducing the organ damage caused by high cholesterol diet.

Keywords: wholesale herbs, natural remedies